The Community-Based Support for Orphans and Vulnerable Children (CUBS) in Nigeria Project is improving the well-being of orphans and vulnerable children in Nigeria by integrating a once fragmented OVC service-delivery system. It has mobilized community support, built local capacities, and raised awareness of the issues and needs of orphans and vulnerable children. Over a five-year period, the project exceeded its original target and reached over 51,000 orphans and vulnerable children with one minimum care package. It has trained 16,000 caregivers and provided sub-grants to 38 civil society organizations to provide services to vulnerable children. CUBS has strengthened community-based vulnerable children service-delivery and supported civil society organizations to initiate and/or reactivate child-protection and vulnerable children interventions in its 11 focal states (Akwa Ibom, Bayelsa, Delta, Rivers, Gombe, Taraba, Kebbi, Sokoto, Ekiti, Enugu, and Imo). It has helped the civil society organizations to develop effective operational policies and procedures and conducted an in-depth analysis of the challenges faced by female vulnerable children to inform evidence-based programming. CUBS also implemented income-generating activities to support female heads of households with vulnerable children. CUBS project was awarded to MSH in partnership with Africare under the AIDSTAR I IQC contract, funded by the President’s Emergency Fund for AIDS Relief (PEPFAR) through the United States Agency for International Development (USAID).